PKA Substrates

Phosphorylation Targets of Protein Kinase A (PKA).   This list includes all basophilic phosphorylation sites found to exhibit a decrease  in phospho-occupancy after CRISPR-Cas9 deletion of both catalytic subunits of PKA (Prkaca and Prkacb) in vasopressin-responsive mouse epithelial cells (mpkCCD). Phospho-occupancy was quantified in PKA double knockout (dKO) vs control (ctrl) cells by LC-MS/MS using SILAC method. Data represent a mean of three biological replicates, i.e. different PKA dKO clones and their respective control lines.   Cells were grown in the presence of the V2 receptor-selective vasopressin analog dDAVP (0.1 nM). Phosphorylation sites may be direct or indirect PKA targets. Site created by Kiyoshi Isobe, Hyun Jun Jung, V. Raghuram, Chin-Rang Yang, Jevin Z. Clark and Mark Knepper of the Division of Intramural Research, NHLBI, Bethesda, Maryland.

Reference: Isobe K, Jung HJ, Yang CR, Claxton J, Sandoval P, Burg MB, Raghuram V, Knepper MA. Systems-level identification of PKA-dependent signaling in epithelial cells. Proc Natl Acad Sci U S A. 2017 Oct PMID: 28973931

For questions and concerns please contact: knepperm@nhlbi.nih.gov


Gene Symbol Mod. Site UniProt Annotation Centralized Sequence Phospho-occupancy (PKA dKO/ctrl)
Cobl S1246 Q5NBX1 Protein cordon-bleu LSLRKVS*SLASEE 0.001
Dcp1a S542 Q91YD3 mRNA-decapping enzyme 1A DLERKAS*S*PSPLT 0.001
Dync1h1 S1228 Q9JHU4 Cytoplasmic dynein 1 heavy chain 1 IMRRKDS*AIQQQV 0.001
Kars S393 Q99MN1 Lysine--tRNA ligase PPFRRIS*MVEELE 0.001
Pbxip1 S164 Q3TVI8 Pre-B-cell leukemia transcription factor-interacting protein 1 RRGREPS*SSQPVV 0.001
Purg S342 Q8R4E6 Purine-rich element-binding protein gamma MDGRRAS*GEEQEC 0.001
Sipa1l1 S1611 Q8C0T5 Signal-induced proliferation-associated 1-like protein 1 LPLRRPS*YTLGMK 0.001
Slc7a6os S156 Q7TPE5 Probable RNA polymerase II nuclear localization protein TDCRKTS*DPDVIL 0.001
Tiam2 S1536 Q6ZPF3 T-lymphoma invasion and metastasis-inducing protein 2 EPSKGNS*LDSDEC 0.001
Tjp1 S168 P39447 Tight junction protein ZO-1 SRERSLS*PRSDRR 0.001
Tmem259 T549 Q8CIV2 Membralin LLERRPT*APSTPD 0.001
Mrpl37 S203 Q921S7 39S ribosomal protein L37, mitochondrial SLARRTS*AQNCTL 0.001
Cgn S326 P59242 Cingulin SVRRKVS*LVLEQM 0.001
Erbb3 S980 Q61526 Receptor tyrosine-protein kinase erbB-3 LVIKRAS*GPGIPP 0.001
Itsn2 S491 Q9Z0R6 Intersectin-2 LSSRKKS*LHLELE 0.002
Zak S567 Q9ESL4 Mitogen-activated protein kinase kinase kinase MLT PGSRSDS*SADCQW 0.002
Hps5 S693 P59438 Hermansky-Pudlak syndrome 5 protein homolog GEGRRVS*LVTEEA 0.002
Borcs6 T201 Q9D6W8 BLOC-1-related complex subunit 6 GGGRRAT*ISSPLE 0.003
Itpr3 S934 P70227 Inositol 1,4,5-trisphosphate receptor type 3 VLSRKQS*VFGASS 0.005
Mtch1 S381 Q791T5 Mitochondrial carrier homolog 1 LLFRRVS*SGSCFA 0.005
Txlng S79 Q8BHN1 Gamma-taxilin GTTKKHS*LEGDEG 0.006
Osbpl11 S179 Q8CI95 Oxysterol-binding protein-related protein 11 LKSRSFS*LASSGN 0.006
Tab2 S524 Q99K90 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 SEARKLS*MGSDDA 0.007
Clip2 S353 Q9Z0H8 CAP-Gly domain-containing linker protein 2 RYARKIS*GTTALQ 0.010
Mrps9 S272 Q9D7N3 28S ribosomal protein S9, mitochondrial SEGRRKS*ATAQAV 0.011
Srp14 S45 P16254 Signal recognition particle 14 kDa protein PIPRKSS*VEGLEP 0.017
Xrn2 S678 Q9DBR1 5'-3' exoribonuclease 2 EENRRNS*LGGDVL 0.019
Tnks1bp1 S429 P58871 182 kDa tankyrase-1-binding protein LAQRRFS*EGVLQP 0.021
Fgd3 S442 O88842 FYVE, RhoGEF and PH domain-containing protein 3 ITGRKRS*LELQTR 0.022
Afap1l2 S484 Q5DTU0 Actin filament-associated protein 1-like 2 LMQRKFS*EPNTYI 0.028
Ccs S267 Q9WU84 Copper chaperone for superoxide dismutase GQGRKDS*AQPPAH 0.029
Plekhf2 S16 Q91WB4 Pleckstrin homology domain-containing family F member 2 ANTRRIS*IVESCF 0.029
Casp8 S188 O89110 Caspase-8 STERRMS*LEGREE 0.036
Irf2bp2 S15 E9Q1P8 Interferon regulatory factor 2-binding protein 2 AASRRQS*CYLCDL 0.040
Sik2 S358 Q8CFH6 Serine/threonine-protein kinase SIK2 GRQRRPS*TIAEQT 0.044
Pi4kb S511 Q8BKC8 Phosphatidylinositol 4-kinase beta DIRRRLS*EQLAHT 0.050
Ablim1 S671 Q8K4G5 Actin-binding LIM protein 1 DPRRRSS*GREEDE 0.055
Snx1 S188 Q9WV80 Sorting nexin-1 AVKRRFS*DFLGLY 0.057
Snx2 S185 Q9CWK8 Sorting nexin-2 SVKRRFS*DFLGLH 0.059
Map3k2 S331 Q61083 Mitogen-activated protein kinase kinase kinase 2 RIRRRGS*DIDNPT 0.067
Lyst S2614 P97412 Lysosomal-trafficking regulator MMQRRMS*QEHPSQ 0.069
Abcc1 S290 O35379 Multidrug resistance-associated protein 1 SKPKGSS*QLDVNE 0.077
Map4k4 S894 P97820 Mitogen-activated protein kinase kinase kinase kinase 4 DPTRKGS*VVNVNP 0.080
Prrc2a S454 Q7TSC1 Protein PRRC2A RQRRKQS*SSEISL 0.085
Wnk1 S2281 P83741 Serine/threonine-protein kinase WNK1 GMARKFS*APGQLC 0.085
Arhgap29 S1149 Q8CGF1 Rho GTPase-activating protein 29 VSERRSS*DSCPAT 0.089
Akap1 S55 O08715 A-kinase anchor protein 1, mitochondrial IKDRRLS*EEACPG 0.092
Veph1 S380 A1A535 Ventricular zone-expressed PH domain-containing protein 1 SSRRKTS*TEVSIP 0.098
Herc4 S830 Q6PAV2 Probable E3 ubiquitin-protein ligase HERC4 LLKRKPS*LDDLKE 0.099
Optn S345 Q8K3K8 Optineurin ALERKNS*ATPSEL 0.104
Pum2 S587 Q80U58 Pumilio homolog 2 SATRRES*LSTSSD 0.118
Bad S155 Q61337 Bcl2-associated agonist of cell death RELRRMS*DEFEGS 0.121
Itpr3 S1832 P70227 Inositol 1,4,5-trisphosphate receptor type 3 TKGRVSS*FSMPSS 0.135
Hectd1 S1389 Q69ZR2 E3 ubiquitin-protein ligase HECTD1 SSSRKGS*SSSVCS 0.138
Prkar2a S96 P12367 cAMP-dependent protein kinase type II-alpha regulatory subunit KFTRRVS*VCAETF 0.144
Fam83h S1035 Q148V8 Protein FAM83H ESPRRPS*LSRGDS* 0.162
Arhgap35 S1150 Q91YM2 Rho GTPase-activating protein 35 ERGRKVS*AVSKPV 0.164
Nfkb1 S940 P25799 Nuclear factor NF-kappa-B p105 subunit TSFRKLS*FTESLT 0.165
Akap1 S101 O08715 A-kinase anchor protein 1, mitochondrial RQVRRRS*ESSGNL 0.181
Arhgef7 S776 Q9ES28 Rho guanine nucleotide exchange factor 7 SRSRKES*APQVLL 0.183
Mpdz S1066 Q8VBX6 Multiple PDZ domain protein AMLRRHS*LIGPDI 0.188
Cad S1406 B2RQC6 CAD protein AGGRRLS*SFVTKG 0.189
C2cd2l S358 Q80X80 C2 domain-containing protein 2-like KVLRSSS*CGDAEL 0.191
Irs1 S1214 P35569 Insulin receptor substrate 1 NSPRRSS*EDLSNY 0.192
Nup133 S37 Q8R0G9 Nuclear pore complex protein Nup133 ASRRGLS*LGSAVN 0.208
Nsfl1c S176 Q9CZ44 NSFL1 cofactor p47 GERRRHS*GQDVHV 0.212
Chchd6 S13 Q91VN4 MICOS complex subunit Mic25 AEARRVS*FEMDEE 0.214
Hspa4 S76 Q61316 Heat shock 70 kDa protein 4 FHGRAFS*DPFVEA 0.216
Plekhg3 S1134 Q4VAC9 Pleckstrin homology domain-containing family G member 3 TSPRRFS*FSPSAV 0.217
Sec23ip S748 Q6NZC7 SEC23-interacting protein ESKRKLS*VGAYVS 0.219
Nhsl1 S1079 Q8CAF4 NHS-like protein 1 RPVRKNS*GAGAVL 0.223
Tbc1d12 S205 Q6A039 TBC1 domain family member 12 EVSRRQS*AGDLLP 0.226
Map4k5 T400 Q8BPM2 Mitogen-activated protein kinase kinase kinase kinase 5 PKPRVNT*YPEDSL 0.228
Sqstm1 S24 Q64337 Sequestosome-1 REIRRFS*FCFSPE 0.229
Map4k5 S433 Q8BPM2 Mitogen-activated protein kinase kinase kinase kinase 5 QVLRRQS*SPSCVP 0.231
Arfgef2 S621 A2A5R2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 DMARRCS*VTSVES 0.231
Nck1 S85 Q99M51 Cytoplasmic protein NCK1 KVKRKPS*VPDTAS 0.233
Golga5 S116 Q9QYE6 Golgin subfamily A member 5 FVRRKKS*EPDDEL 0.237
Casp6 S62 O08738 Caspase-6 NLTRRFS*DLGFEV 0.238
Tjp2 T540 Q9Z0U1 Tight junction protein ZO-2 QILKVNT*QDFRGL 0.241
Arhgap17 S698 Q3UIA2 Rho GTPase-activating protein 17 PGMRRCS*SSLPPI 0.245
Bloc1s5 S23 Q8R015 Biogenesis of lysosome-related organelles complex 1 subunit 5 GGKKRDS*LGTPGA 0.252
Ctnnb1 S552 Q02248 Catenin beta-1 DTQRRTS*MGGTQQ 0.255
Vipas39 T21 Q8BGQ1 Spermatogenesis-defective protein 39 homolog SKFKAFT*FDDEDD 0.256
Eif2ak2 S110 Q03963 Interferon-induced, double-stranded RNA-activated protein kinase AQKKKLS*VNYEQC 0.258
Pum1 S710 Q80U78 Pumilio homolog 1 SGSRRDS*LTGSSD 0.259
Tnks1bp1 S887 P58871 182 kDa tankyrase-1-binding protein EFGKRAS*VSTNQD 0.262
Myo9b S1647 Q9QY06 Unconventional myosin-IXb YTGRRKS*ELGAEP 0.262
Lrrfip1 S88 Q3UZ39 Leucine-rich repeat flightless-interacting protein 1 TSSRRGS*GDTSIS 0.265
Eif4b S442 Q8BGD9 Eukaryotic translation initiation factor 4B NTRRRES*EKS*LEN 0.266
Fbl S130 P35550 rRNA 2'-O-methyltransferase fibrillarin YGEKRVS*ISEGDD 0.266
Reps1 S272 O54916 RalBP1-associated Eps domain-containing protein 1 NEIRRQS*SSYEDP 0.268
Nfatc2 S257 Q60591 Nuclear factor of activated T-cells, cytoplasmic 2 GAKRRHS*CAEALV 0.273
Saysd1 S16 Q8K190 SAYSvFN domain-containing protein 1 EARKRAS*LVAQPS 0.276
Clip2 S974 Q9Z0H8 CAP-Gly domain-containing linker protein 2 SEQRRYS*LIDPAS 0.276
Irs2 S556 P81122 Insulin receptor substrate 2 RPYRRVS*GDGAQD 0.276
Lmna S301 P48678 Prelamin-A/C SRIRIDS*LSAQLS 0.280
Fam83h S970 Q148V8 Protein FAM83H VPERRGS*LTFAGE 0.286
Tns3 S363 Q5SSZ5 Tensin-3 VRKKSAS*DTGIPS 0.291
Specc1l S385 Q2KN98 Cytospin-A ERSRKGS*SGNASE 0.296
Mib2 S251 Q8R516 E3 ubiquitin-protein ligase MIB2 ELQRRVS*ADGQPF 0.298
Limch1 S377 Q3UH68 LIM and calponin homology domains-containing protein 1 WKSRRRS*ASQDLI 0.304
Cgnl1 S298 Q6AW69 Cingulin-like protein 1 ARSRRSS*SSSTTP 0.306
Snx12 S73 O70493 Sorting nexin-12 CVRRRYS*DFEWLK 0.312
Wwc1 S141 Q5SXA9 Protein KIBRA WEHKLGS*QVSLVS 0.313
Slain2 T314 Q8CI08 SLAIN motif-containing protein 2 NSTRRGT*FSDQEL 0.313
Ncor1 S1459 Q60974 Nuclear receptor corepressor 1 VRARHTS*VVSSGP 0.316
Ybx3 S328 Q9JKB3 Y-box-binding protein 3 YNYRRRS*RPLNAV 0.317
Tns3 S361 Q5SSZ5 Tensin-3 AKVRKKS*ASDTGI 0.320
Wdr4 T48 Q9EP82 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 TAEKKAT*PEDKGE 0.321
Wdtc1 S511 Q80ZK9 WD and tetratricopeptide repeats protein 1 STSRKDS*ISEDEM 0.324
Skt S528 A2AQ25 Sickle tail protein EKPRNTS*GLSSLV 0.326
Klc3 S173 Q91W40 Kinesin light chain 3 SPPRRDS*LASLFP 0.332
Tomm34 S93 Q9CYG7 Mitochondrial import receptor subunit TOM34 PLLRRAS*AYEALE 0.333
Fkbp15 S1091 Q6P9Q6 FK506-binding protein 15 GNSRRLS*LTPDPE 0.336
Arhgap27 S459 A2AB59 Rho GTPase-activating protein 27 RSVRKSS*QDSDTP 0.337
Lima1 S225 Q9ERG0 LIM domain and actin-binding protein 1 AGGRRLS*ENNCSL 0.344
Ppm1h S123 Q3UYC0 Protein phosphatase 1H NSKRRSS*LPNGEG 0.346
Pcm1 S384 Q9R0L6 Pericentriolar material 1 protein SQSRNPS*VSEHLP 0.348
Ptpn13 S929 Q64512 Tyrosine-protein phosphatase non-receptor type 13 EILKRLS*SSEWSL 0.352
Mark2 S409 Q05512 Serine/threonine-protein kinase MARK2 PKQRRSS*DQAVPA 0.356
Osbpl11 S177 Q8CI95 Oxysterol-binding protein-related protein 11 PPLKSRS*FSLASS 0.361
Dennd4c S987 A6H8H2 DENN domain-containing protein 4C SIVKVPS*GLFDTN 0.362
Arpp19 S104 P56212 cAMP-regulated phosphoprotein 19 LPQRKPS*LVASKL 0.375
Reps1 S536 O54916 RalBP1-associated Eps domain-containing protein 1 TRQRSHS*GTSPDN 0.376
Specc1l S386 Q2KN98 Cytospin-A RSRKGSS*GNASEV 0.376
Sorbs2 S339 Q3UTJ2 Sorbin and SH3 domain-containing protein 2 FRKRRKS*EPAVGP 0.394
Pcyt1b S335 Q811Q9 Choline-phosphate cytidylyltransferase B SPSRSPS*PTFSWL 0.395
Myo5b S1614 P21271 Unconventional myosin-Vb YRKRSSS*MVDGEN 0.395
Pard6b S31 Q9JK83 Partitioning defective 6 homolog beta AEFRRFS*LERSKP 0.401
Scyl2 S677 Q8CFE4 SCY1-like protein 2 GKQKRGS*LTLEEK 0.402
Veph1 S507 A1A535 Ventricular zone-expressed PH domain-containing protein 1 SPLRNSS*ASHPS*I 0.406
Hectd1 S1390 Q69ZR2 E3 ubiquitin-protein ligase HECTD1 SSRKGSS*S*SVCSV 0.411
Rtkn S106 Q8C6B2 Rhotekin KTGRRPS*DSVQPA 0.412
Znf608 S439 Q56A10 Zinc finger protein 608 RGKRARS*AAAAPG 0.414
Psmf1 S153 Q8BHL8 Proteasome inhibitor PI31 subunit EKARANS*PPREFP 0.416
Sufu S346 Q9Z0P7 Suppressor of fused homolog APSRKDS*LGSDSS 0.417
Sufu S342 Q9Z0P7 Suppressor of fused homolog THDRAPS*RKDS*LG 0.417
Ctnna1 T654 P26231 Catenin alpha-1 FDVRS*RT*S*VQTED 0.420
Sptbn1 T2327 Q62261 Spectrin beta chain, non-erythrocytic 1 ASSRAQT*LPTSVV 0.420
Kiaa1522 S317 A2A7S8 Uncharacterized protein KIAA1522 SSLRTLS*RCS*LLS 0.420
Osbpl10 S190 S4R1M9 Oxysterol-binding protein-related protein 10 PGSRSRS*LTLLPH 0.423
Plekhg3 S737 Q4VAC9 Pleckstrin homology domain-containing family G member 3 SFSRRS*S*LAIEDG 0.426
Arhgap21 S1655 Q6DFV3 Rho GTPase-activating protein 21 RVSRRNS*EGS*EAS 0.427
Erbin S1150 Q80TH2 Erbin IPERTMS*VSDFNY 0.431
Kiaa1109 S1320 A2AAE1 Uncharacterized protein KIAA1109 CSTRLGS*TKS*LTA 0.447
Pitpnm3 S295 Q3UHE1 Membrane-associated phosphatidylinositol transfer protein 3 SSSRKGS*ISSTQD 0.453
Mef2d S180 Q63943 Myocyte-specific enhancer factor 2D TDPRLLS*PQQPAL 0.456
Tns2 S830 Q8CGB6 Tensin-2 HSPRAGS*VS*PGSP 0.458
Veph1 S449 A1A535 Ventricular zone-expressed PH domain-containing protein 1 RFSRSRS*LALNTV 0.460
Yap1 S382 P46938 Transcriptional coactivator YAP1 YHSRDES*TDSGLS 0.461
Wdfy3 S3317 Q6VNB8 WD repeat and FYVE domain-containing protein 3 DDSRRWS*DQLSLD 0.462
Ap3d1 S754 O54774 AP-3 complex subunit delta-1 KGKRRHS*SLPTES* 0.463
Dopey1 S1140 Q8BL99 Protein dopey-1 HMAKASS*PDDDVQ 0.464
Agps S52 Q8C0I1 Alkyldihydroxyacetonephosphate synthase, peroxisomal KARRAAS*AAGASP 0.468
Fkbp15 S342 Q6P9Q6 FK506-binding protein 15 PGLRS*KS*NSLSEQ 0.470
Rpl18a S123 P62717 60S ribosomal protein L18a HRARAHS*IQIMKV 0.470
Spire2 S445 Q8K1S6 Protein spire homolog 2 KRDRSFS*EHDLAQ 0.472
Dock1 S1756 Q8BUR4 Dedicator of cytokinesis protein 1 GNERRFS*VSPASP 0.475
Enah S637 Q03173 Protein enabled homolog AKLRKVS*RVEDGS 0.476
Mia3 S1915 Q8BI84 Melanoma inhibitory activity protein 3 EEAKPAS*PS*SVQD 0.476
Tiam1 S695 Q60610 T-lymphoma invasion and metastasis-inducing protein 1 RRSRFSS*LWGLDT 0.477
Pxn S533 Q8VI36 Paxillin YHERRGS*LCSGCQ 0.483
Sik2 S587 Q8CFH6 Serine/threonine-protein kinase SIK2 REGRRAS*DTSLTQ 0.485
Mical3 S685 Q8CJ19 Protein-methionine sulfoxide oxidase MICAL3 GKRRKTS*QSEEEE 0.486
Nf1 S2599 Q04690 Neurofibromin PHLRKVS*VSESNV 0.486
Skt S353 A2AQ25 Sickle tail protein PRDRLSS*LPVSRS 0.488
Wnk1 S2367 P83741 Serine/threonine-protein kinase WNK1 NLQKSIS*NPPGSN 0.491
Map2 S1352 P20357 Microtubule-associated protein 2 AEPKDGS*PDAPAT 0.491
Clmn S419 Q8C5W0 Calmin DGRRSNS*LPVKKT 0.492
Dopey1 S1261 Q8BL99 Protein dopey-1 SRQRSHS*SIQFSF 0.492
Nek4 S430 Q9Z1J2 Serine/threonine-protein kinase Nek4 LLPRRSS*DGGDGE 0.492
Ptpn13 S901 Q64512 Tyrosine-protein phosphatase non-receptor type 13 NMGRAIS*TGS*LAS 0.493
Tnks1bp1 S866 P58871 182 kDa tankyrase-1-binding protein EFGKRDS*LGS*FST 0.500
Pard3 S715 Q99NH2 Partitioning defective 3 homolog DRERRIS*HSLYSG 0.501
Smarcad1 S79 Q04692 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 DNERKAS*LSCFQN 0.503
Osbp S377 Q3B7Z2 Oxysterol-binding protein 1 GHKRTGS*NIS*GAS* 0.504
Ctnnd1 S861 P30999 Catenin delta-1 NASRSQS*SHS*YDD 0.505
Phldb2 S510 Q8K1N2 Pleckstrin homology-like domain family B member 2 RCHRKGS*LQDVDV 0.505
Map3k5 S973 O35099 Mitogen-activated protein kinase kinase kinase 5 EYLRSIS*LPVPVL 0.507
Pi4ka S260 E9Q3L2 Phosphatidylinositol 4-kinase alpha LKRKTSS*VSS*ISQ 0.510
Arhgef2 S885 Q60875 Rho guanine nucleotide exchange factor 2 LDPRRRS*LPAGDA 0.511
Fkbp15 S344 Q6P9Q6 FK506-binding protein 15 LRS*KSNS*LSEQLT 0.511
Src S17 P05480 Neuronal proto-oncogene tyrosine-protein kinase Src ASQRRRS*LEPSEN 0.516
Peak1 S818 Q69Z38 Pseudopodium-enriched atypical kinase 1 PPVRPKS*LFTSQS 0.517
Kazn S350 Q69ZS8 Kazrin PRHRTHS*LCNGDS 0.518
Chd9 S549 Q8BYH8 Chromodomain-helicase-DNA-binding protein 9 NIPRVMS*PENFPS 0.522
Arhgef17 S142 Q80U35 Rho guanine nucleotide exchange factor 17 PSSRRPS*MDSEAL 0.522
Rin1 S446 Q921Q7 Ras and Rab interactor 1 RLRRRLS*ADGSLG 0.523
Shroom3 S285 Q9QXN0 Protein Shroom3 ARERSGS*MDVISA 0.529
Baiap2 S367 Q8BKX1 Brain-specific angiogenesis inhibitor 1-associated protein 2 TLPRSSS*MAAGLE 0.535
Atp6v0a2 S695 P15920 V-type proton ATPase 116 kDa subunit a isoform 2 TLVRKDS*EEEVS*L 0.535
Jup S665 Q02257 Junction plakoglobin DYRKRVS*VELTNS* 0.541
Rab11fip1 S340 Q9D620 Rab11 family-interacting protein 1 SEIRESS*PSNSPS 0.542
Zhx1 S45 P70121 Zinc fingers and homeoboxes protein 1 ENAKAES*VS*S*DEE 0.543
Map4k3 S329 Q99JP0 Mitogen-activated protein kinase kinase kinase kinase 3 REEKTRS*EINFGQ 0.543
Lsr S448 Q99KG5 Lipolysis-stimulated lipoprotein receptor DINRPGS*TESGRS 0.547
Arhgap17 S484 Q3UIA2 Rho GTPase-activating protein 17 ERKRPAS*MAVMEG 0.547
Atg2b S379 Q80XK6 Autophagy-related protein 2 homolog B YYLRKDS*LSMGVS 0.547
Klhdc7a S361 A2APT9 Kelch domain-containing protein 7A GFSRKVS*LLQIAE 0.552
Cobll1 S384 Q3UMF0 Cordon-bleu protein-like 1 IMVRTGS*LQLS*ST 0.553
Borcs6 S130 Q9D6W8 BLOC-1-related complex subunit 6 RVCRRGS*PGGVEM 0.555
Pkn2 S621 Q8BWW9 Serine/threonine-protein kinase N2 LRPKSKS*EYELSI 0.556
Zzef1 S1464 Q5SSH7 Zinc finger ZZ-type and EF-hand domain-containing protein 1 RRQRTSS*VVEEHF 0.557
Eif5b S183 Q05D44 Eukaryotic translation initiation factor 5B ERSRVNS*S*GES*GG 0.557
Dock7 S898 Q8R1A4 Dedicator of cytokinesis protein 7 NRSRSLS*NSNPDI 0.567
Ssh1 S585 Q76I79 Protein phosphatase Slingshot homolog 1 SKPRSDS*LPQVEE 0.568
Igsf5 S335 Q7TSN7 Immunoglobulin superfamily member 5 PEKRSSS*LPYQEL 0.570
Uhrf1bp1l S1108 A2RSJ4 UHRF1-binding protein 1-like NMKRSAS*QVS*LDT 0.573
Map3k2 S153 Q61083 Mitogen-activated protein kinase kinase kinase 2 ERKKRLS*VVGPPN 0.575
Hbp1 S380 Q8R316 HMG box-containing protein 1 ARQRRAS*LSCGGG 0.577
null S255 Q91Z58 Uncharacterized protein C6orf132 homolog AITKWKS*EVALNG 0.579
Larp4b S500 Q6A0A2 La-related protein 4B GRGRKNS*FGYRKK 0.580
Bnip2 S114 O54940 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 EVIRKGS*ITEYTA 0.581
Mtor S2448 Q9JLN9 Serine/threonine-protein kinase mTOR SRTRTDS*YSAGQS* 0.583
Vill S234 Q91YD6 Villin-like protein LGCRSGS*LCPSVP 0.584
Rab18 S144 P35293 Ras-related protein Rab-18 KFARKHS*MLFIEA 0.585
Camk2d T331 Q6PHZ2 Calcium/calmodulin-dependent protein kinase type II subunit delta DGVKEST*ESSNTT 0.588
Myo9b S1325 Q9QY06 Unconventional myosin-IXb TEERRIS*FSTSDI 0.588
Rbm14 T206 Q8C2Q3 RNA-binding protein 14 GQARQPT*PPFFGR 0.588
Pdlim2 S134 Q8R1G6 PDZ and LIM domain protein 2 LSPRPCS*PFSTPP 0.591
Ptpn14 S833 Q62130 Tyrosine-protein phosphatase non-receptor type 14 VKERPVS*EMFSLE 0.592
Prkd2 S197 Q8BZ03 Serine/threonine-protein kinase D2 ARKRRLS*STSLAS 0.597
Baiap2 S455 Q8BKX1 Brain-specific angiogenesis inhibitor 1-associated protein 2 QQGKSSS*TGNLLD 0.598
Eps8l1 S182 Q8R5F8 Epidermal growth factor receptor kinase substrate 8-like protein 1 ELRRGAS*PAAETP 0.599